In this meticulous study, Wouter Hanegraaff examines the structure, themes, and development of Emanuel Swedenborg's massive work _Secrets of Heaven_, published between 1749 and 1756. Written as a work of biblical exegesis, Swedenborg also interpolated material on his visionary experiences, which have long fascinated readers. In the second part of the study, Dr. Hanegraaff examines the contemporary reception of the multi-volume work, particularly the critical reactions of Immanuel Kant and Friedrich Christoph Oetinger. He finds that Swedenborg's biblical exegesis, so (...) important in his divine calling, was largely ignored in favor of the mystical experiences. (shrink)

The innovative field of Regenerative Medicine (RM) is expected to extend the possibilities of prevention or early treatment in healthcare. Increasingly, clinical trials will be developed for people at risk of disease to investigate these RM interventions. These individuals at risk are characterised by their susceptibility for developing clinically manifest disease in future due to the existence of degenerative abnormalities. So far, there has been little debate about the ethical appropriateness of including such individuals at risk in clinical trials. We (...) discuss three main challenges of selecting this participant model for testing RM interventions: the challenge of achieving a proportional risk–benefit balance; complexities in the trial design in terms of follow-up and sample size; and the difficulty of obtaining informed consent due to the many uncertainties. We conclude that selecting the model is not ethically justifiable for first-in-man trials with RM interventions due to the high risks and uncertainties. However, the model can be ethically appropriate for testing the efficacy of RM interventions under the following conditions: interventions should be low risk; the degenerative abnormalities (and other risk factors) should be strongly related with disease within a short time frame; robust preclinical evidence of efficacy needs to be present; and the informed consent procedure should contain extra safeguards with regard to communication on uncertainties. (shrink)

\noindent\textbf{Introduction} Online interventions hold great potential for Therapeutic Change Process Research (TCPR), a field that aims to relate in-therapeutic change processes to the outcomes of interventions. Online a client is treated essentially through the language their counsellor uses, therefore the verbal interaction contains many important ingredients that bring about change. TCPR faces two challenges: how to derive meaningful change processes from texts, and secondly, how to assess these complex, varied and multi-layered processes? We advocate the use text mining and multi-level (...) models (MLMs): the former offers tools and methods to discovers patterns in texts; the latter can analyse these change processes as outcomes that vary at multiple levels. \noindent\textbf{Method} We (re-)used the data from \cite{Lamers2015} because it includes outcomes and the complete online intervention for clients with mild depressive symptoms. We used text mining to obtain basic text-variables from e-mails, that we analysed through MLMs. \noindent\textbf{Results} We found that we could relate outcomes of interventions to variables containing text-information. We conclude that we can indeed bridge text mining and MLMs for TCPR as it was possible to relate text-information (obtained through text mining) to multi-levelled TCPR outcomes (using a MLM). \noindent\textbf{Discussion} Text mining can be helpful to obtain change processes, which is also the main challenge for TCPR. We showed how MLMs and text mining can be combined, but our proposition leaves open how to obtain the most relevant textual operationalization of TCPR concepts. That requires interdisciplinary collaboration and discussion. The future does look bright: based on our proof-of-concept study we conclude that MLMs and text mining can indeed advance TCPR. (shrink)

Cross‐strand disulphides (CSDs) are unusual bonds that link adjacent strands in the same β‐sheet. Their peculiarity relates to the high potential energy stored in these bonds, both as torsional energy in the highly strained disulphide linkage and as deformation energy stored in the sheet itself. CSDs are relatively rare in protein structures but are conspicuous by their presence in proteins that are involved in cell entry. The finding that entry of botulinum neurotoxin and HIV into mammalian cells involves cleavage of (...) CSDs suggests that the activity of other cell entry proteins may likewise involve cleavage of these bonds. We examine emerging evidence of the involvement of these unusual disulphides in cell entry events. BioEssays 26:73–79, 2004. © 2003 Wiley Periodicals, Inc. (shrink)

The introduction of novel diagnostic techniques in clinical domains such as genomics and radiology has led to a rich ethical debate on how to handle unsolicited findings that result from these innovations. Yet while unsolicited findings arise in both genomics and radiology, most of the relevant literature to date has tended to focus on only one of these domains. In this article, we synthesize and critically assess similarities and differences between “scanning the body” and “sequencing the genome” from an ethical (...) perspective. After briefly describing the novel diagnostic contexts leading to unsolicited findings, we synthesize and reflect on six core ethical issues that relate to both specialties: terminology; benefits and risks; autonomy; disclosure of unsolicited findings to children; uncertainty; and filters and routine screening. We identify ethical rationales that pertain to both fields and may contribute to more ethically sound policies. Considerations of preserving public trust and ensuring that people perceive healthcare policies as fair also support the need for a combined debate. (shrink)

An increasing number of older patients have to decide on a treatment plan for advanced chronic kidney disease, involving dialysis or conservative care. Shared decision-making is recommended as the model for decision-making in such preference-sensitive decisions. The aim of SDM is to come to decisions that are consistent with the patient’s values and preferences and made by the patient and healthcare professional working together. In clinical practice, however, SDM appears to be not yet routine and needs further implementation. A shift (...) from a biomedical to a person-centered conception might help to make the process more shared. Shared should, therefore, be interpreted as two persons bringing two perspectives to the table, that both need to be explored during the decision-making process. Starting from the patient’s perspective will enable to determine the mutual goals of care first and, subsequently, determine the best way for achieving those goals. To perform such SDM, the healthcare professional needs to become a skilled companion, being part of the patient’s relational context, and start asking the right questions about what matters to the patient as person. In this article, we describe the need for a person-centered conception of SDM for the setting of older patients with advanced CKD. (shrink)

In this paper, we introduce the Societal Readiness Thinking Tool to aid researchers and innovators in developing research projects with greater responsiveness to societal values, needs, and expectations. The need for societally-focused approaches to research and innovation—complementary to Technology Readiness frameworks—is presented. Insights from responsible research and innovation concepts and practice, organized across critical stages of project-life cycles are discussed with reference to the development of the SR Thinking Tool. The tool is designed to complement not only shortfalls in TR (...) approaches, but also improve upon other efforts to integrate RRI, sustainability, and design thinking in research and innovation cycles. Operationalization and early-stage user tests of the Tool are reported, along with discussion of potential future iterations and applications. (shrink)

The aim of this empirical study is to understand how bachelor students at universities of applied sciences (UAS) use their ethical compasses during internships. Semi-structured interviews were held with 36 fourth-year bachelor students across four UAS and three different programs in the Netherlands: Initial Teacher Education, Business Services, and Information and Communication Technology. To our knowledge, no studies appear to have investigated and compared students from multiple professional fields, nor identified the dynamics and the sequence of the strategies in the (...) decision-making process that students use when faced with ethical dilemmas during internships. We found that students’ ethical dilemmas stemmed from: mentors’ or managers’ behaviours/requests, colleagues’ behaviours, organisations’ morally questionable incentives, pupils’ home situations, and pupils’ behaviours/personal stories. The majority of students used multiple strategies and first investigated the ethical dilemmas they encountered and then avoided, intervened, delegated responsibilities, or adjusted to their environments. Students’ values played an important role in experiencing an ethical dilemma, however, these values were not always acted upon. We identified that rather students’ beliefs about having influence and/or ownership (or not), personal interest(s) and power relations influenced the way how they used their ethical compasses. Thus, instead of navigating on moral standards (of their profession), students reacted on beliefs which reflected the ways in which they constructed their internship contexts, social relationships and their own (and others) needs. As a result, half of the mentioned dilemmas were resolved in a prudent-strategic manner (e.g., by prioritising personal interests), instead of morally. This indicates that students did not always convert (moral) values into moral action and did not use their ethical compasses in the way UAS aspires. Finally, this study found that the ways in which students used their ethical compasses were strongly influenced by their environments. (shrink)

In this empirical study, we investigate _what_ and _how_ teachers in Dutch universities of applied sciences (UAS) think they contribute to the development of students’ ethical compasses. Six focus groups were conducted with teachers across three programmes: Initial Teaching Education, Business Services, and Information and Communication Technology. This study revealed that teachers across the three different professional disciplines shared similar ideas about what should be addressed in the development of students’ ethical compasses. Their contributions were grouped into three core themes: (...) creating students’ moral awareness, developing students’ moral skills and promoting students’ moral professional behaviour. The majority of the teachers used a wide range of planned and unplanned pedagogic–didactic actions (reflecting individual learning and cooperative and group learning) to enhance the development of students’ ethical compasses. However, teachers’ strategies were mostly unstructured and unreflective and depended on the individual teacher’s ability and knowledge to address moral themes. Furthermore, the study revealed two incompatible ideals: as role models, the teachers aimed to exemplify explicitly how to be a professional with an ethical compass. However, they also wanted to adopt a neutral stance because they were afraid to manipulate the students’ ethical compasses. Therefore, they avoided promoting _the_ ethical compass that they believed to be the best. (shrink)

“Esotericism” refers, more or less, to what used to be called “the occult.” It comprises such matters as astrology, alchemy, kabbalism, magic, and theosophy—to name just a few. In other words, it refers to just about everything that came to be marginalized in the modern period as “superstition” and “pseudo-science,” and anathematized by scientists and philosophers. In recent decades, there has been an explosion of scholarly interest in esotericism, partly because of research revealing that many “canonical” scientists and philosophers of (...) the past were strongly interested in these “irrational” currents. The philosophers include Leibniz, Kant, Hegel, Schelling, and Schopenhauer; the scientists include Newton. Such .. (shrink)

Ontological pluralism is the view that there are ways of being. In this paper, we build a new case for ontological pluralism in the form of three contributions: (1) We offer a theoretically useful definition of ‘way of being’ as a positive principle of similarity and difference that is distinct from—and a prior condition for—having properties. (2) We develop a test for distinguishing ways of being from properties: features of entities that are conceptually redundant when represented as predicates in standard (...) predicate logic are ways of being. Finally, (3) we argue that there are ways of being, i.e., there are features of entities that satisfy the definition in (1), and pass the test outlined in (2). Along the way, we reply to objections against pluralism raised by Peter van Inwagen and Wouter Cohen, in an attempt to show that pluralism is well-motivated. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Virtue Ethics for the Real World: Improving Character without Idealization by Howard J. CurzerBenjamin HoleCURZER, Howard J. Virtue Ethics for the Real World: Improving Character without Idealization. New York: Routledge, 2023. 272 pp. Cloth, $160.00The development of virtue ethics has been in a lull. This book is a welcome treatise in theory-building, developing a novel Aristotelian approach to virtue ethics that, first, avoids idealization and, second, provides a (...) method for character improvement. It is divided into two parts reflecting these themes.The front matter before the title page brandishes a "No Don Quixotes" sign, warning the reader the following pages are no place for a misguided idealist. Part 1, "Against Idealization," contains six chapters. Chapter 2 argues that idealization is not a useful guide, but an impediment to virtue, since ideals can be misleading, psychologically damaging, and used for nefarious purposes. Chapters 3 through 7 construct a virtue ethical theory without idealization. Idealization may seem central to a virtue-oriented approach to ethics. For example, Rosalind Hursthouse's famous biconditional claims that an act is right if and only if it is what the virtuous person would characteristically do in the same circumstances. By contrast, chapter 3 provides counterexamples separating virtuous action from what the virtuous person would characteristically do, and separating virtuous action from right action. Sacrificing Hursthouse's biconditional is a fundamental change to the way many conceive of Aristotelian virtue ethics, demanding revisions to the rest of the theory. For instance, to address moral dilemmas, chapter 4 defends two psychological mechanisms under which there are virtuous, morally wrong acts that are admirably immoral, and vicious, morally right acts that leave the agent with dirty hands.Chapter 5 provides the grounding for contemporary Aristotelian virtue ethics without idealization, by answering what makes character traits [End Page 541] virtues and what makes acts virtuous. Two-level eudaimonism involves a thin theory, where virtue consists in responding well to different spheres of human activity, and a thick theory, where responding well contributes to the agent's eudaimonia. Since virtuous people may characteristically perform nonvirtuous actions, virtuous actions are not necessarily what virtuous people characteristically do but actions that are endorsed by virtuous people from the perspective of virtue. The "Perspectives Doctrine" claims that virtuous people decide how to respond from the perspective of different virtues, and those perspectives offer incomplete and sometimes incompatible ways of responding. For instance, a temperate person endorsing an action as temperate from the perspective of temperance makes it temperate, but would not make it courageous, and an endorsement from the perspective of courage would not make her action temperate. Agents determine what is virtuous by asking virtuous people to consider, from the perspective of virtue, what should be done; when virtuous people are unavailable, agents can consult philosophers and social scientists who research the responses of virtuous people. Chapter 6 rejects the "Reciprocity of the Virtue Doctrine," which claims possessing one virtue entails possessing the rest, in favor of the "Unevenly Virtuous People Doctrine," on which people can have some but not all of the virtues; character typically improves at different paces in different areas of life. Chapter 7 rejects Philippa Foot's "Corrective Doctrine" of virtue as implausible idealization in favor of a traditionally Aristotelian "Doctrine of the Mean," and argues that the virtues of integrity, forgiveness, tolerance, open-mindedness, and civility are governed by that doctrine.Although character improvement seems to depend on idealization, by striving to achieve some end, part 2's five chapters paint an alternative picture. Chapter 8 defends a medical analogy over competing models philosophers typically employ to understand character improvement, including skill (Aristotle and Julia Annas), stage or path (Aristotle and Wouter Sanderse), self-cultivation (Mengzi), and self-construction (Xunzi) analogies. To improve character, one must look to a fine-grained list of possible character flaws, diagnose deficits in character, and then heal character flaws by employing targeted strategies, including "inculcation strategies, rehabilitation strategies, and strategies to improve society's ethical climate." Character improvement is complex and becomes more so when considering all of the ways one might err. Chapter 9 introduces an Aristotelian model for moral decision-making within each... (shrink)

Intentional action is, in some sense, non-accidental, and one common way action theorists have attempted to explain this is with reference to control. The idea, in short, is that intentional action implicates control, and control precludes accidentality. But in virtue of what, exactly, would exercising control over an action suffice to make it non-accidental in whatever sense is required for the action to be intentional? One interesting and prima facie plausible idea that we wish to explore in this paper is (...) that control is non-accidental in virtue of requiring knowledge – either knowledge-that or knowledge-how (e.g., Beddor and Pavese 2021; cf., Setiya 2008; 2012 and Habgood-Coote 2018). We review in detail some key recent work defending such knowledge-centric theories of control, and we show that none of these accounts holds water. We conclude with some discussion about how control opposes the sort of luck intentional action excludes without doing so by requiring knowledge (that- or how). (shrink)

On Humour and the Comic in the Hebrew Bible. Edited by Y. T. Radday and A. Brenner.The Trouble With Kings: The Composition of rhe Book of Kings in the Deuteronomistic History. By Steven L. McKenzie.Sacred Space: An Approach to the Zheology of the Epistle to the Hebrews. By Marie E. Isaacs.Fourth Ezra: A Commentary on the Book of Fourth Ezra. By Michael Edward StonePaul the Convert: iShe Apostolate and Apostasy of Saul the Pharisee. By Alan F. Segal.Creative Biblical Exegesis: Christian (...) and Jewish Hermeneutics through the Centuries. Edited by Benjamin Uffenheimer and Henning Graf Reventlow.The Hope of the Early Church: A Handbook of Patristic Escharology. By Brian E. Daley.The Emergence of the Laity in the Early Church. By Alexandre Faivre, translated by David Smith.Pastoral Life and Practice in the Early Church. By Carl A. Volz.The Making of the Creeds. By Frances Young.La correzione fratenia in s. Agosrino. By Agostino Clerici.Beaup and Revelation in the Thought of St Augustine. By Carol Harrison.Grace, Politics and Desire. Edited by Hugo Meynell.Boerhius and Aquinas. By Ralph McInerny.The Weight of Glory. A Vision and Practice for Christian Faith: The Future of Liberal Theology. Edited by D. W. Hardy and P. H. Sedgwick.Atonenrent and Incarnation. By Vernon White.Tragic Method and Tragic Theology: Evil in Contemporary Drama and Religious Thought. By L. D. Bouchard.Parmenides of Elea, Fragments: A Text and Translation, with an Introduction. By David Gallop.Language, Thought and Falsehood in Ancient Greek Philosophy. By Nicholas Denyer.Weakness of the Will. By Justin Gosling.Knowledge and the Sciences in Medieval Philosophy. Vol. I, edited by Monica Asztalos, John E. Murdoch and Ilkka Niiniluoto.Episcopal Power and Norenrine Sociev. 1000–1320. By George W. Dameron.Matins, Lauds and Vespers for St David's Day. By Owain Tudor Edwards.More's ‘Utopia’. By Dominic Baker‐Smith.Frontiers of Heresy: The Spanish Inquisitionfrom the Basque Lands to Sicily. By William Monter.Inquisition and Society in the Kingdom of Valencia, 1478–1834, By Stephen Haliczer.The Fear of Hell: Images of Damnation and Salvation in Early Modern Europe. By Piero Camporesi, translated by Lucinda Byatt.Lucrecia's Dreams: Politics and Prophecy in Sixteenth‐Centun Spain. By Richard L. Kagan.Heresy and Mysticism in Sixteenth‐Century Spain: The Alumbrados. By Alastair Hamilton.Japan's Encounter with Christianiry: The Catholic Mission in Pre‐Modern Japan. By Neil S. Fujita.Galileo, Bellannine and the Bible. By Richard J.Augustine Baker's Inner Light: A Study in English Recusant Spirituality. By James Gaffney.The Prorestarit Evaqelical Awakening. By W. R. Ward.The Study of Anglicanism. Edited by Stephen Sykes and John Booty.The Anglican Tradition: A Handbook of Sources. Edited by G. R. Evans and J. Robert Wright.The Restoration Church of England, 1646‐1689. By John Spurr.Awash in a Sea of Faith: Christianizing the American People. By Jon Butler.A Woman Styled Bold: The Life of Cornelia Connelly, 1809–1879. By Radegunde Flaxman.Cane Ridge: America's Pentecost. By Paul K. Conkin.Revivalism and Social Change: Christianio, Nation Building and the Market in the Nineteenth‐Century United States. By George M. Thomas.Church and State: The English Experience. By Adrian Hastings.Evelyn Underhill: Artist of the Infinite Life. By Dana Greene.Northern Ireland: Fairh and Faction. By Maurice Irvine.The Tragedy of Belief: Division, Politics, arid Religion in Ireland. By John Fulton.Shattered Vows: Exodus from the Priesthood. By David Rice.Making Saints: Inside the Vatican: Who Become Saints, Who Do Not, and Why. By Kenneth L. Woodward.Ecclesiae Memoria: Miscellanea in onorr del R. P. Josef Metzler, O. M. I. Edited by Willi Henkel. (shrink)

“What do you see when you look at your face in the mirror?” asks J. David Velleman in introducing his philosophical theory of action. He takes this simple act of self-scrutiny as a model for the reflective reasoning of rational agents: our efforts to understand our existence and conduct are aided by our efforts to make it intelligible. Reflective reasoning, Velleman argues, constitutes practical reasoning. By applying this conception, _Practical Reflection_ develops philosophical accounts of intention, free will, and the foundation (...) of morals. This new edition of _Practical Reflection_ contains the original 1989 text along with a new introduction and is the latest entry in The David Hume Series of Philosophy and Cognitive Science Reissues, which keeps in print previously published indispensable works in the area of cognitive science. _ _ _ _. (shrink)

While the opposing paradigms of globalization and fragmentation compete in often bloody and destructive ways in the world today, this book convincingly reminds us of the importance of finding out more about the complex and changing ways in which we are connected. The authors demonstrate that the more we understand our connectedness and deal with its consequences, the less dependent and helpless we become. The critical, multidisciplinary perspectives they offer cover a wide range of subjects, from the world wide web (...) to medieval poetry, nations and gender, cancer narratives and money, emotion management and the financial markets, and the American civilizing process and the repression of shame. The contributions bear witness to Elias's innovative achievements while the authors continue his stunning explorations, extending them into other areas of the humanities and the sciences, and presenting their own wide-ranging and penetrating insights into our mutual dependence. Contributors are Jorge Arditi, Godfried Van Benthem Van Den Bergh, Reinhard Blomert, Stephen Guy-Bray, Thomas M. Kemple, Hermann Korte, Helmut Kuzmics, Stephen Mennell, Thomas Salumets, Thomas J. Scheff, Ulrich C. Teucher, Annette Treibel, and Cas Wouters. (shrink)

Built in the centre of Copenhagen, and noted for its equestrian stairway, the Rundetaarn, was intended as an astronomical observatory. Part of a complex of buildings that once included a university library, it affords expansive views of the city in every direction, towering above what surrounds it. The metaphor of the towering figure, who sees what others might not, whose vantage point allows him to visualize how things fit together, and who has an earned-stature of respect and authority, fits another (...) Danish stalwart, Hans Vilhelm Hansen, whose contributions to the fields of informal logic and argument theory have earned the gratitude of his colleagues, and inspired this collection of essays, written to express the appreciation of its authors and of the many, many colleagues they represent. (shrink)

J J Schwieso, N J Hastings; Explanations and Practice: behaviour modification in education, Journal of Philosophy of Education, Volume 20, Issue 1, 30 May 2006.

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Philosophy 41.3 (2003) 407 [Access article in PDF] Reply By Margaret J. Osler and Richard A. Watson In his comments on our historiographical Notes in the October 2002 issue of JHP, A. P. Martinich misrepresents our position by erroneously claiming that we presume a sharp dichotomy between the analytic history of philosophy and the historical history of philosophy. Neither of us accepts such a (...) premise. Once that misreading is eliminated there are few disagreements between each of us and Martinich.We agree that any meaningful history of philosophy must be both philosophically sophisticated and historically grounded. History without philosophy would be nothing but chronicle; history of philosophy without historical context would describe a series of moves, but explain nothing. A desideratum of both history and philosophy is careful reading, exposition, and analysis of texts.... (shrink)

The research project described in this report represents one of the most extensive studies of character education ever undertaken, including over 10,000 students and 255 teachers in schools across England, Scotland, Northern Ireland and Wales. Research techniques consisted of a mixture of surveys, moral dilemmas and semi-structured interviews. This report explores: - The current situation in character education, both in the UK and internationally - How developed British students are with respect to moral character and the extent to which they (...) are able to understand and apply moral virtues, especially those aged 14 and 15 - How teachers in the UK understand their role in terms of students’ moral and character development - What helps or hinders the development of children’s characters according to teachers in UK schools. (shrink)

This chapter focuses on the question of quantitativeness – of identifying the feature that makes quantitative properties quantitative. The chapter begins with two traditional attempts at capturing what makes a property quantitative – being numerical and being determinable – and argues that neither is satisfactory. The chapter then turns to influential recent proposals which, inspired by the Representational Theory of Measurement, attempt to identify particular relations as characteristic of quantitative properties. These attempts fare better than the traditional ones, but have (...) their own limitations. It concludes with a discussion of a new recent criterion for quantitativeness, which builds on a more abstract understanding of the representational theory of measurement. (shrink)